The San Francisco 49ers (5-4) will take on the Arizona Cardinals (4-6) in the major NFC West Division competition on Monday Night Football at Estadio Azteca in Mexico City.
The 49ers lead the NFL All-Time Series 32-29, but the Cardinals have won three of the last four contests between teams.
Everything you need in terms of betting on a 49ers vs Cardinals match is here: points spreads, moneylines, total over/under, expert picks (odds with FOX betting) and more.
Nick Wright reacts to the 49ers’ 16-22 victory over the Chargers.
Nick Wright talks about the 49ers’ 16-22 win over the Chargers on Sunday Night Football.
Related: Weekend Soccer Gambling Roundup
49ers versus. cardinals Mexico City (ESPN, Monday at 8:15 PM)
Point Spread: 49ers -8 (49ers favored winning by 8 points or more, Cardinals covered otherwise)
Moneyline: 49ers -400 favorites win (bet $10 to win a total of $12.50); Cardinals +280 Underdog wins (bet $10 to win a total of $38)
Total Points Over/Under: 43.5 points for both teams
San Francisco 49ers
Choose from gambling analysts Sam Panayotovic:
This is basically an elimination game for NFC West.
Oddsmakers don’t really believe Arizona given the spread of points, and it’s very difficult to bet on a team led by Kliff Kingsbury in one fell swoop. I don’t have a record of winning against
Wild, isn’t it?
Meanwhile, the Niners’ offense is near full power, and if Christian McCaffrey, Deebo Samuel, George Kittle, and Brandon Ayuk stay healthy together on the field, they’re going to be in trouble. I don’t like laying down that much chalk, but it’s the right move.
Don’t be surprised if Arizona loses by two touchdowns.
Pick: 49ers (-8 on FOX bet) Win by 8 points or more
Ready to bet on the NFL? If so, head over to FOX Bet for all your bets.
Download the FOX Super 6 App It’s your chance to win thousands of dollars in the biggest sporting events of the week! Just select and win the Grand Prix. Download and play now!
Enjoy more National Football League Follow your favorites to stay informed about games, news and more